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  • Crinetics presented up to two-year PATHFNDR-1/2 data confirming PALSONIFY maintains durable acromegaly biochemical control.
  • IGF-1 levels remained stable and acromegaly symptoms were controlled across patients.
  • PALSONIFY stabilized or reduced pituitary tumor volume in the extension studies.
  • Patients switched from injectable therapies and previously untreated patients both showed durable responses.
  • Combining PALSONIFY with cabergoline improved biochemical control versus PALSONIFY alone.
  • No new safety signals were reported, supporting tolerability and market relevance of oral paltusotine.

Latest Articles

Guterres Proposes Three Configurations for Post-2024 UN Presence in Lebanon

Guterres Proposes Three Configurations for Post-2024 UN Presence in Lebanon

U.N. Secretary-General Antonio Guterres has presented three distinct options to the U.N. Security Council for maintaining a uniformed U.N. presence in Lebanon after the U.N. Interim Force in Lebanon (UNIFIL) mandate expires at year-end. The proposals, submitted in a letter to the Council, vary in size and capability, and all would support a strengt…

Fighting Rekindles Around Gulf as Diplomacy Stalls Between Tehran and Washington

Fighting Rekindles Around Gulf as Diplomacy Stalls Between Tehran and Washington

Hostilities flared again in the Gulf region as Kuwait and Bahrain reported missile and drone alerts while the United States fired on a tanker bound for Iran. Explosions were reported near Qeshm Island and maritime traffic through the Strait of Hormuz remains largely halted. Diplomatic efforts between Iran and the United States are reported to have …

Nurix Therapeutics Executive Activity and Clinical Data Signals

Nurix Therapeutics Executive Activity and Clinical Data Signals

Nurix Therapeutics' Chief Legal Officer, Christine Ring, recently sold a significant amount of common stock through an established Rule 10b5-1 trading plan. Simultaneously, the company generated substantial investor interest by presenting promising clinical data for its drug candidates, leading several major analyst firms to revise their ratings an…

Bayer Says It Will Not Spin Off Monsanto as Litigation Mounts

Bayer Says It Will Not Spin Off Monsanto as Litigation Mounts

In remarks at the Wall Street Journal’s Global Food Forum, a Bayer representative said the company has no current plans to separate Monsanto despite facing roughly 100,000 Roundup-related lawsuits. Chief Executive Bill Anderson warned that unresolved litigation could halt American production of glyphosate, and the company continues to pursue settle…

Executive Sale at Dianthus Therapeutics Signals Internal Adjustments

Executive Sale at Dianthus Therapeutics Signals Internal Adjustments

Simrat Randhawa, Executive Vice President and Head of Research & Development at Dianthus Therapeutics, Inc., executed a transaction involving the sale of approximately $2.4 million worth of company common stock on June 1, 2026. These sales were conducted under a pre-arranged Rule 10b5-1 trading plan following the exercise of stock options. The arti…

Director's Purchase Activity and Strategic Updates at Star Equity Holdings

Director's Purchase Activity and Strategic Updates at Star Equity Holdings

A director of Star Equity Holdings purchased additional shares of common stock in late May 2026. This transaction occurs against a backdrop of ongoing corporate activities, including an At Market Issuance Sales Agreement for preferred stock, updated executive compensation plans, and the completion of a significant sale-leaseback transaction involvi…

Zenas BioPharma Announces Data from the Registrational Phase 3 INDIGO Trial of Obexelimab in Immunoglobulin G4-Related Disease (IgG4-RD), Simultaneously Presented at the EULAR 2026 Congress and Published in the New England Journal of Medicine

Zenas BioPharma Announces Data from the Registrational Phase 3 INDIGO Trial of Obexelimab in Immunoglobulin G4-Related Disease (IgG4-RD), Simultaneously Presented at the EULAR 2026 Congress and Published in the New England Journal of Medicine

Zenas BioPharma announced positive Phase 3 INDIGO trial results for obexelimab in treating Immunoglobulin G4-Related Disease (IgG4-RD). The trial met its primary and all key secondary endpoints with statistically significant reductions in disease flare risk, glucocorticoid use, and related toxicities. Obexelimab demonstrated a favorable safety prof…

Director's Buy Signal at Phibro Animal Health Amid Mixed Market Signals

Director's Buy Signal at Phibro Animal Health Amid Mixed Market Signals

Phibro Animal Health Corp. director E. Thomas Corcoran recently acquired 10,000 shares of the company's Class A Common Stock on May 29, 2026, valued at $317,700. This transaction occurred while the stock was trading down significantly over the past week. The purchase comes against a backdrop where the firm reported strong financial results for the …

Director's Sale and Strategic Developments at Rambus Inc. (RMBS)

Director's Sale and Strategic Developments at Rambus Inc. (RMBS)

Rambus director, Eric B. Stang, sold a significant block of company shares totaling $730,000 on June 1, 2026. This transaction occurred against a backdrop of positive corporate developments for Rambus Inc., including the introduction of new AI-enabled components and upgrades to its financial guidance from major investment banks.

Quest Diagnostics CEO's Stock Sale and Recent Company Developments

Quest Diagnostics CEO's Stock Sale and Recent Company Developments

J. E. Davis, the CEO and President of Quest Diagnostics Inc., completed a sale of company stock valued at approximately $1.94 million on June 1, 2026. This transaction occurred while the stock traded near $193.16. Beyond this executive action, the company has announced significant financial developments, including a quarterly cash dividend and a la…