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  • Crinetics presented up to two-year PATHFNDR-1/2 data confirming PALSONIFY maintains durable acromegaly biochemical control.
  • IGF-1 levels remained stable and acromegaly symptoms were controlled across patients.
  • PALSONIFY stabilized or reduced pituitary tumor volume in the extension studies.
  • Patients switched from injectable therapies and previously untreated patients both showed durable responses.
  • Combining PALSONIFY with cabergoline improved biochemical control versus PALSONIFY alone.
  • No new safety signals were reported, supporting tolerability and market relevance of oral paltusotine.

Latest Articles

Extreme Networks Officer Sells Significant Stake in Company Stock

Extreme Networks Officer Sells Significant Stake in Company Stock

Katayoun Motiey, Chief Legal Admin Sust Officer at Extreme Networks Inc. (NASDAQ:EXTR), sold a total of 15,000 shares of the company's common stock worth $427,500 over two consecutive trading days in June 2026. These sales occurred while EXTR stock is near its 52-week high and following recent reports of strong financial performance and positive an…

CopperTech Metals Seeks U.S. Listing After Revenue Leap, Outlines Use of IPO Proceeds for Konkola Expansion

CopperTech Metals Seeks U.S. Listing After Revenue Leap, Outlines Use of IPO Proceeds for Konkola Expansion

CopperTech Metals filed for a U.S. initial public offering after reporting a marked increase in revenue from its Konkola Copper Mines operations. The company, established by Vedanta Resources to hold and run the Zambian asset, plans to list on the New York Stock Exchange under the ticker CUX and aims to deploy primary IPO proceeds toward production…

Lotus opens orders for Eletre X in mainland Europe

Lotus opens orders for Eletre X in mainland Europe

Lotus Technology Inc. announced the launch of the Eletre X, an advanced hybrid SUV featuring proprietary X-Hybrid architecture that combines electric performance with an onboard generator powered by a turbo engine. Offering over 1,200 km total range and fast 9-minute charging, the vehicle delivers supercar-level performance and practical SUV functi…

Fortrea to Attend Jefferies Global Healthcare Conference

Fortrea to Attend Jefferies Global Healthcare Conference

Fortrea, a global contract research organization, announced that its CEO, CFO, and SVP of Investor Relations will participate in the Jefferies Global Healthcare Conference. The company provides comprehensive clinical development solutions, partnering with biopharmaceutical, biotechnology, medical device, and diagnostic companies worldwide.

SpaceX Poised to Set IPO Terms, Aims for $1.8 Trillion Valuation

SpaceX Poised to Set IPO Terms, Aims for $1.8 Trillion Valuation

SpaceX is moving toward formally setting terms for its planned initial public offering, with an amended filing expected to reveal the price range and number of shares for sale. The company is seeking to raise up to $75 billion and is targeting a valuation of at least $1.8 trillion, with a short roadshow and possible pricing as soon as June 11.

Ameresco Director Sells Shares Following Options Exercise; Company Reports Major Infrastructure and JV Developments

Ameresco Director Sells Shares Following Options Exercise; Company Reports Major Infrastructure and JV Developments

A filing revealed that Ameresco director Francis V. Wisneski Jr. sold 5,000 shares of the company on May 29, 2026, for a total value of $180,600. This sale occurred after he acquired an equal number of shares through the exercise of stock options. These transactions take place against a backdrop of Ameresco's significant operational achievements, i…

Radian Group CEO-Elect's Significant Stock Acquisition Signals Confidence

Radian Group CEO-Elect's Significant Stock Acquisition Signals Confidence

Radian Group Inc.'s Chief Executive Officer-elect, Michael S. Weinbach, recently increased his personal investment in the company by acquiring an additional 170,000 shares. This activity comes amid positive corporate developments for Radian Group, including strong first quarter earnings, a dividend announcement, and significant leadership changes w…

Moody's Lowers Whirlpool's Unsecured Debt Rating After Second-Lien Upsize

Moody's Lowers Whirlpool's Unsecured Debt Rating After Second-Lien Upsize

Moody's has downgraded the senior unsecured notes ratings for Whirlpool Corporation and its guaranteed borrowers to B2 from B1, citing greater effective subordination after the company's upsized secured second-lien issuance. Other ratings, including the Ba3 Corporate Family Rating and the Ba1 rating on the senior secured second-lien notes, were lef…

U.S. Strike Disables Botswana-Flagged Tanker En Route to Iran

U.S. Strike Disables Botswana-Flagged Tanker En Route to Iran

The U.S. military fired a Hellfire missile at the Botswana-flagged tanker M/T Lexie on June 2, Central Command said, striking the ship’s engine room after the crew failed to comply with repeated warnings over a 24-hour period. The action is part of a blockade that the U.S. says it imposed to pressure Iran into negotiating on terms set by President …

Fade the Deal-Led Rerate: Short TLN After Acquisition Pop

Fade the Deal-Led Rerate: Short TLN After Acquisition Pop

Talen Energy (TLN) has seen a fresh repricing after regulatory clearances for a three-plant acquisition and the earlier pricing of $4 billion in senior notes. The fundamentals — high leverage, elevated valuation multiples, and a large near-term capacity add financed with long-dated debt — leave the stock vulnerable to a mean-reversion move. This tr…