Stock Markets April 19, 2026 08:40 PM

Eli Lilly Nears Deal to Buy Kelonia Therapeutics for Over $2 Billion, Sources Say

Negotiations advance on acquisition of CAR-T developer focused on multiple myeloma; transaction may include milestone payments

By Leila Farooq LLY
Eli Lilly Nears Deal to Buy Kelonia Therapeutics for Over $2 Billion, Sources Say
LLY

Eli Lilly is in advanced discussions to acquire private biotech Kelonia Therapeutics for more than $2 billion, according to people familiar with the talks. The deal - which could be announced as soon as Monday if negotiations hold - would bolster Lilly's oncology pipeline by adding a next-generation CAR-T candidate aimed at multiple myeloma. The transaction may include contingent, milestone-based payments. Kelonia has raised just under $60 million and was valued slightly above $100 million in 2022.

Key Points

  • Eli Lilly is in advanced talks to acquire Kelonia Therapeutics for more than $2 billion; an announcement could come as soon as Monday if negotiations remain on track.
  • The acquisition may include milestone-based payments in addition to upfront consideration.
  • Kelonia is developing a simplified CAR-T therapy for multiple myeloma and has raised just under $60 million, with a last recorded valuation slightly above $100 million in 2022; the deal would expand Lilly's oncology pipeline and presence in blood cancers.

Eli Lilly is reported to be in advanced negotiations to acquire Kelonia Therapeutics for a price in excess of $2 billion, according to people familiar with the matter. Those involved in the discussions indicated the companies could announce an agreement as soon as Monday, provided the talks do not break down.

The contemplated purchase price may not be limited to an upfront payment - the structure is said to potentially include additional payments tied to development or regulatory milestones.

Kelonia is a privately held biotechnology company developing a next-generation treatment for multiple myeloma, a form of blood cancer. The company is advancing a novel CAR-T therapy designed to reprogram a patients immune system to attack malignant cells. The approach under development emphasizes simplification, with the stated goal of avoiding both chemotherapy and the complex cell-manufacturing processes typically associated with CAR-T therapies.

Financially, Kelonia has raised just under $60 million to date. The firms most recent valuation, recorded in 2022, was slightly above $100 million.

For Eli Lilly, acquiring Kelonia would reinforce its position in the blood cancer segment and broaden its oncology pipeline. The reported discussions come amid an active period of dealmaking for Lilly, which has been pursuing acquisitions supported by strong cash flows from its high-selling weight-loss and diabetes medications.


Context and implications

While details of any definitive agreement remain subject to negotiation, the elements disclosed so far highlight three themes: a significant headline price above $2 billion, possible contingent milestone payments that would tie future payouts to clinical or regulatory progress, and a strategic fit related to CAR-T therapies for multiple myeloma. Because Kelonia is privately held and has raised limited capital relative to the reported purchase price, the transaction would represent a substantial valuation uplift compared with its last recorded value in 2022.

Market participants and industry observers will likely watch for confirmation of the announced timing and for any specifics on payment structure and governance, should a deal be finalized.

Risks

  • Negotiations could collapse - the companies may fail to reach a final agreement, which would halt the transaction and any immediate strategic benefits.
  • The inclusion of milestone-based payments implies contingent future obligations tied to clinical or regulatory milestones, creating uncertainty about total deal cost and future financial impact.
  • Kelonia's status as a privately held company with limited capital raised and a prior valuation just above $100 million means there is uncertainty around integration value and the trajectory needed to justify the reported acquisition price.

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