Passage Bio Reports Updated Interim Data from upliFT-D Trial and Provides Regulatory and Corporate Updates
Passage Bio announced updated interim data from its Phase 1/2 upliFT-D trial of PBFT02 for frontotemporal dementia with GRN mutations, showing reductions in brain atrophy and stabilization of plasma neurofilament levels in early-stage patients. Despite encouraging biomarker improvements and safety profile, the FDA requires a randomized controlled t…