Insider Trading May 28, 2026 04:11 PM

Insider Activity and Earnings Review for Twist Bioscience Corp (NASDAQ:TWST)

CEO sells stock following option exercises; recent earnings show revenue growth but miss on EPS.

By Derek Hwang TWST

Twist Bioscience CEO, Emily M. Leproust, executed transactions involving the sale of company common stock totaling approximately $3.21 million over two days in late May 2026, utilizing a pre-arranged Rule 10b5-1 trading plan. These sales occurred as the stock was approaching its 52-week high and following recent earnings reports that highlighted strong year-over-year revenue growth but also noted an earnings per share (EPS) miss.

Insider Activity and Earnings Review for Twist Bioscience Corp (NASDAQ:TWST)
TWST

Key Points

  • Insider selling: CEO Emily M. Leproust sold approximately $3.21 million worth of stock over two days using a Rule 10b5-1 plan.
  • Mixed financial results: The company reported strong revenue growth (19% YoY increase to $111 million) but missed analyst expectations on Earnings Per Share (EPS).
  • Analyst upgrades and projections: Despite the EPS miss, analysts like TD Cowen raised price targets following the revenue beat, with management projecting revenues near $1 billion by FY 2031.

Insider Transactions at Twist Bioscience

Emily M. Leproust, Chief Executive Officer of Twist Bioscience Corp (NASDAQ:TWST), recently completed several transactions involving the sale of company common stock. These sales amounted to approximately $3.21 million and took place across May 26 and May 27, 2026. It is important to note that these dispositions were carried out under a pre-arranged Rule 10b5-1 trading plan.

The timing of the sales was notable as the stock price was nearing its 52-week high of $66.94, following substantial appreciation of 127% over the preceding year. Analysis from InvestingPro suggested that at current market levels, the stock appeared to be overvalued relative to its calculated Fair Value.

Details of Stock Sales

On May 26, Ms. Leproust first acquired 24,282 shares of Twist Bioscience common stock by exercising employee options, with each option priced at $8.82 per share. She subsequently sold the entire block of 24,282 shares at a weighted average price of $65.0789 per share. The specific sale prices for this initial set of shares varied between $65.00 and $65.505.

The following day, May 27, further transactions were recorded. Ms. Leproust acquired an additional 25,017 shares through option exercises, also at the rate of $8.82 per share. Of this newly acquired stock, she sold 23,752 shares with a weighted average price of $65.2392 per share. The sale prices for this portion spanned from $65.00 to $65.93.

In addition to the first tranche of sales, another segment of 1,265 shares was sold on May 27 at a weighted average price of $66.2813 per share. The pricing range for these final shares was between $66.09 and $66.72.

In aggregate, across both days, Ms. Leproust exercised options to acquire 49,299 shares at a cumulative cost of $434,817. She then liquidated all 49,299 shares for a combined total value of $3,213,653. Following these transactions, her direct ownership stake in Twist Bioscience common stock was reported to stand at 846,872 shares.

Recent Financial Performance and Analyst Coverage

Separately, the company released its second-quarter fiscal year 2026 earnings report. The results indicated robust revenue growth, achieving total revenues of $111 million. This figure represents a 19% increase compared to the previous year and surpassed the consensus estimate of $108 million.

Despite the positive top-line performance, the reported Earnings Per Share (EPS) was -$0.71, which fell short of the forecasted negative earnings per share of -$0.48. These results prompted immediate reactions from investment analysts and increased management projections for the future.

Analyst Reactions and Future Guidance

Following the announcement, TD Cowen revised its price target for Twist Bioscience to $68, up from a previous level of $58. The firm maintained its Buy rating, citing the revenue beat as a primary factor supporting the increase in valuation. Similarly, Leerink elevated its price target to $80, an increase from $70, while retaining an Outperform rating subsequent to the company's Investor Day.

During the Investor Day event, Twist Bioscience management provided projections suggesting that total revenue is expected to reach approximately $1 billion by fiscal year 2031. This projection implies a compound annual growth rate exceeding 16%, reflecting a positive outlook from the company's leadership despite the recent shortfall in EPS.

Market Context

The stock continued its upward trajectory after the reported transactions, climbing to $69.03, which marked a 6% increase when compared to the sale prices executed by the CEO. The market data provided further context, showing the price had climbed to $69.70 in After Hours trading, representing a 0.97% gain.

Risks

  • Earnings Miss Risk: The reported negative EPS of -$0.71 significantly missed the consensus forecast of -$0.48, which could weigh on investor sentiment.
  • Valuation Uncertainty: One analysis noted that the stock appeared overvalued relative to its Fair Value at current market levels.
  • High Growth Dependency: Future valuation is heavily tied to management's aggressive projection of reaching $1 billion in revenue by FY 2031, which carries execution risk.

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