Allogene Therapeutics Reports Interim Futility Analysis from Pivotal ALPHA3 Trial Showing 58.3% MRD Clearance with Cemacabtagene Ansegedleucel (Cema-Cel) vs. 16.7% in Observation Arm in First-Line Consolidation LBCL
Allogene Therapeutics announced encouraging interim futility analysis results from its Phase 2 ALPHA3 trial evaluating cemacabtagene ansegedleucel (cema-cel), an allogeneic CAR T therapy, in first-line consolidation for large B-cell lymphoma (LBCL). The cema-cel arm showed a 58.3% minimal residual disease (MRD) clearance rate versus 16.7% in the ob…