Stock Markets February 26, 2026

XSpray Resubmits Dasynoc to FDA, Eyes Two Oncology Launches in H2 2026

Swedish drug developer sets a latest possible PDUFA date of August 2026 and reiterates plans to bring two cancer therapies to the U.S. market in the second half of 2026

By Priya Menon
XSpray Resubmits Dasynoc to FDA, Eyes Two Oncology Launches in H2 2026

XSpray Pharma has re-filed its U.S. marketing application for Dasynoc with the Food and Drug Administration and expects a Prescription Drug User Fee Act (PDUFA) date to be assigned no later than August 2026. The company reaffirmed its timeline to introduce two oncology products in the second half of 2026 - Dasynoc and XS003 nilotinib - after addressing prior regulatory requirements related to the Dasynoc submission.

Key Points

  • XSpray has re-submitted its FDA application for Dasynoc and expects a PDUFA date by August 2026 at the latest - impacts healthcare and biotech sectors.
  • The company reaffirmed plans to launch two oncology products - Dasynoc and XS003 nilotinib - in the second half of 2026, affecting oncology-focused pipelines and U.S. market commercialization activities.
  • The resubmission follows efforts to address prior regulatory requirements, underlining the central role of regulatory review timelines for drug developers and investors in pharmaceuticals.

XSpray Pharma AB confirmed on Thursday that it has re-submitted its application to the U.S. Food and Drug Administration for Dasynoc. The company said it has worked to address regulatory matters cited previously and has now filed an updated application for review.

In a statement, XSpray said it expects the FDA to assign a new Prescription Drug User Fee Act - PDUFA - date by August 2026 at the latest. The PDUFA date establishes the FDA's formal deadline for completing its review of the drug application.

Alongside the resubmission news, the Swedish drugmaker reiterated its commercial timeline, maintaining plans to launch two products in the second half of 2026. Those planned launches are Dasynoc and XS003 nilotinib, both intended for the U.S. market and positioned within XSpray's oncology-focused portfolio.

Dasynoc is described by the company as a candidate intended to serve as an alternative treatment option. The resubmission follows a period during which XSpray worked to meet regulatory requirements identified in earlier interactions with the FDA.

XS003 nilotinib is identified as the second product in the company's U.S. development pipeline. XSpray framed both assets as part of its focus on oncology therapies for the U.S. market.


Context and next steps

The company is now awaiting an official PDUFA date from the FDA, which will set the agency's internal target for completing its review of the Dasynoc application. XSpray has not provided additional dates beyond the statement that August 2026 is the latest expected PDUFA assignment.

Management has kept its previously announced goal of introducing two products in the latter half of 2026, signaling continued focus on regulatory progress and product launches for its oncology portfolio.

Summary of announcements

  • Dasynoc resubmitted to the U.S. FDA.
  • Company expects a PDUFA date to be set by August 2026 at the latest.
  • XSpray maintains plans to launch Dasynoc and XS003 nilotinib in the second half of 2026.

Risks

  • Regulatory uncertainty remains until the FDA assigns and completes review by the PDUFA date, which affects the timing of potential approval and launch - relevant to healthcare and biotech markets.
  • The application was resubmitted after addressing previous regulatory requirements, indicating there is still risk tied to whether the FDA will accept the resubmission and grant approval - a regulatory and commercialization risk for pharmaceuticals.
  • Timing risk around the planned launches in the second half of 2026, as successful commercial introduction depends on regulatory outcomes and the FDA review process - pertinent to market entry and commercialization in the healthcare sector.

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