Stock Markets February 25, 2026

GSK to Buy 35Pharma for $950 Million to Broaden Cardiopulmonary and Obesity-Linked Pipeline

U.K. drugmaker adds early-stage HS235 program as it pursues treatments tied to obesity under CEO Luke Miels

By Hana Yamamoto GSK
GSK to Buy 35Pharma for $950 Million to Broaden Cardiopulmonary and Obesity-Linked Pipeline
GSK

GSK has agreed to acquire Canada-based 35Pharma for $950 million, incorporating a cardiopulmonary drug candidate, HS235, into its pipeline. The acquisition is described by the companies as complementary to GSK's push into conditions associated with obesity and is one of several deals pursued under CEO Luke Miels to bolster the company’s drug portfolio.

Key Points

  • GSK will acquire Canada-based 35Pharma for $950 million, adding cardiopulmonary treatments to its pipeline.
  • 35Pharma’s lead candidate, HS235, is in early-stage development for multiple types of pulmonary hypertension and is reported by the companies to have potential metabolic benefits, including fat loss.
  • The transaction is part of dealmaking activity under GSK chief executive Luke Miels as the company seeks to strengthen its drug pipeline in areas connected to obesity.

GSK has reached an agreement to acquire 35Pharma, a biopharmaceutical company based in Canada, for $950 million, the two companies announced. The transaction brings cardiopulmonary assets into GSK’s portfolio and aligns with the drugmaker’s stated effort to expand its focus on diseases connected to obesity.

35Pharma’s lead candidate, HS235, is in early-stage development for multiple forms of pulmonary hypertension. According to statements from the companies involved, the drug’s mechanism may also offer metabolic advantages, including fat loss, though those benefits remain described as potential at this stage.

The deal is the latest acquisition executed while Luke Miels serves as chief executive of GSK. Company commentary highlights this transaction as part of a broader push to strengthen the drug pipeline under his leadership.

From a strategic perspective, the acquisition directly adds cardiopulmonary research and development capability to GSK’s existing therapeutic focus. The addition of HS235 gives the buyer an early-stage candidate aimed at pulmonary hypertension and a possible avenue into metabolic effects that companies link to obesity-related conditions.

Market observers will likely watch how GSK integrates 35Pharma’s programs and advances HS235 through development, but the companies’ public statements emphasize the potential of the candidate to address cardiopulmonary disease while also showing metabolic promise.


Sector and market implications

  • Pharmaceuticals and biotechnology - adds early-stage cardiopulmonary assets to an established drugmaker.
  • Healthcare - increases focus on therapies associated with obesity-related conditions.

Risks

  • HS235 is in early-stage development, which implies clinical and regulatory uncertainty for the program - this primarily impacts the pharmaceutical and biotech sectors.
  • Metabolic benefits of HS235 are described as potential by the companies, indicating uncertainty about whether those effects will be confirmed through development - this affects obesity-related therapeutic strategies in healthcare.

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