Stock Markets February 17, 2026

CSL Grants Exclusive License to Eli Lilly for Heart and Kidney Drug; Shares Tick Higher

Agreement provides $100 million upfront to CSL for clazakizumab and possible future payments as shares recover after last week's sell-off

By Marcus Reed CSL LLY
CSL Grants Exclusive License to Eli Lilly for Heart and Kidney Drug; Shares Tick Higher
CSL LLY

CSL Ltd has entered an exclusive licensing agreement with Eli Lilly for clazakizumab, a treatment targeting heart and kidney disease. CSL will receive a $100 million upfront payment and may collect milestone payments and royalties. The announcement coincided with a modest intraday rise in CSL shares after the stock had plunged nearly 17% the previous week amid weak first-half results and a top-management change.

Key Points

  • CSL has granted Eli Lilly exclusive rights to develop and commercialize clazakizumab for heart and kidney disease.
  • CSL will receive a $100 million upfront payment and could earn clinical and commercial milestone payments plus royalties on global sales.
  • CSL shares rose as much as 2% to A$154.21, contributing to a 0.4% gain for the ASX 200, after the stock fell nearly 17% the prior week following weak first-half earnings and a leadership change.

CSL Ltd said on Wednesday it has agreed to license its clazakizumab treatment to Eli Lilly and Company under an exclusive development and commercialization arrangement for heart and kidney disease. The agreement grants Eli Lilly rights to advance and market the drug globally.

Under the terms disclosed, CSL will receive an upfront cash payment of $100 million. The company is also eligible to obtain additional clinical and commercial milestone payments tied to future progress, along with royalties on worldwide sales should the product reach the market.

The market reaction was positive: CSL shares gained as much as 2% to A$154.21 during trading, a move that helped push the ASX 200 up about 0.4% on the session. The share price bounce followed a steep pullback last week, when CSL stock fell nearly 17% after the company reported weak first-half earnings and announced a change in its top leadership.

Investors in CSL have been navigating the aftermath of the earnings update and executive reshuffle, and the licensing deal with Eli Lilly provides a near-term cash infusion plus potential upside from future milestones and royalty streams. The company did not disclose the maximum potential value of milestone payments or the exact royalty rates in its announcement.

For market-watchers, the pairing of an immediate $100 million payment with contingent payments and royalties is the central financial takeaway from the agreement. The licensing move transfers development and commercialization responsibilities to Eli Lilly while preserving for CSL future revenue exposure if clazakizumab advances through clinical and regulatory stages and eventually reaches commercial sales.


Contextual note: CSL's share recovery on the news was partial, restoring some ground lost during the prior week's sell-off but not erasing that decline. The company's performance and leadership changes remain immediate factors for investors alongside the newly announced licensing arrangement.

Risks

  • The deal’s future value depends on clinical and commercial milestones and eventual market sales, which are uncertain - impacts biotech and healthcare sectors.
  • CSL’s recent nearly 17% share decline following weak earnings and a top leadership change signals lingering investor concerns about the company’s near-term performance - impacts equity market sentiment for CSL and related ASX biotech names.
  • The announcement did not disclose the maximum milestone payments or royalty rates, leaving the ultimate financial benefit to CSL unclear - affects investor assessment of CSL’s future cash flows.

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