Stock Markets February 10, 2026

AstraZeneca Sees 2026 Sales and Profit Growth as It Builds Pipeline and Expands in U.S. and China

Company pins 2026 upside on cancer portfolio and newer medicines while navigating policy shifts and regional investments

By Maya Rios AZN
AstraZeneca Sees 2026 Sales and Profit Growth as It Builds Pipeline and Expands in U.S. and China
AZN

AstraZeneca said it expects mid-to-high single-digit revenue growth and low double-digit core profit growth in 2026, driven by demand for cancer therapies and newer drugs alongside expansion efforts in the United States and China. The Anglo-Swedish drugmaker reported modest revenue growth in the latest quarter and outlined strategic investments including a $50 billion U.S. manufacturing deal, an NYSE listing, and a $15 billion China commitment.

Key Points

  • AstraZeneca forecasts 2026 revenue growth of mid-to-high single-digit percentages at constant currency and core profit growth in the low double digits.
  • The company reported Q4 core EPS of $2.12 and revenue of $15.50 billion, in line with the company-compiled analyst consensus.
  • Strategic expansion efforts include a $50 billion U.S. manufacturing deal, an NYSE listing, and a $15 billion investment in China; oncology sales were a major contributor to recent growth.

Feb 10 - AstraZeneca on Tuesday projected higher profit and sales in 2026, citing strength in its oncology portfolio and momentum for newer treatments as it steps up expansion in its two largest markets, the United States and China. The guidance forms part of CEO Pascal Soriot's plan to push the company toward an $80 billion annual sales target by 2030 through new medicines and targeted investments, even as U.S. tariff and healthcare policy changes remain an uncertainty.

The company said it expects total revenue in 2026 to rise by a mid-to-high single-digit percentage on a constant currency basis, and for core profit to increase by a low double-digit percentage. These projections follow a year in which AstraZeneca's sales and profit climbed 8% and 11%, respectively.

For the three months ended December 31, AstraZeneca reported core earnings per share of $2.12, with total revenue up 2% to $15.50 billion. Those results matched the company-compiled analyst consensus of $2.12 per share and roughly $15.4 billion in revenue.

Drug-specific performance in the quarter showed a 20% increase in cancer drug sales to $7.03 billion, while revenue from cardiovascular medicines fell 6% to $3.05 billion, a decline AstraZeneca attributed in part to generic competition.

The group has pursued several large-scale moves to strengthen its position in the United States and China. In the U.S., AstraZeneca last year agreed a $50 billion manufacturing arrangement and listed on the New York Stock Exchange. In China, after encountering regional setbacks, the company is pursuing a $15 billion investment this year to deepen its footprint.

Earlier company guidance had anticipated revenue expanding by a high single-digit percentage and core earnings growing by a low double-digit percentage; the newly announced 2026 target reiterates management's expectation of continued top-line and core-profit progress over the next few years.

Separately, retail-facing promotional material questioned whether investors should buy AZN today, pointing to an AI-driven screening tool that evaluates thousands of companies monthly using more than 100 financial metrics to identify stocks with favorable risk-reward profiles. The promotional note cited past winners identified by the tool but did not change the company-reported financials or outlook.


Data points

  • 2026 revenue outlook: mid-to-high single-digit percentage growth at constant currency
  • 2026 core profit outlook: low double-digit percentage growth
  • 2025 results: sales up 8%, profit up 11%
  • Quarter to Dec 31: core EPS $2.12; total revenue $15.50 billion, up 2%
  • Cancer drugs quarterly sales: $7.03 billion, up 20%
  • Cardiovascular drugs quarterly sales: $3.05 billion, down 6%
  • Major investments: $50 billion U.S. manufacturing deal; NYSE listing; $15 billion China investment

Risks

  • Shifting U.S. tariff and healthcare policies could affect the company's U.S. operations and profitability - this impacts the pharmaceuticals and healthcare sectors.
  • Generic competition has contributed to a 6% decline in cardiovascular drug revenue, representing a product-specific commercial risk that affects revenue stability in the pharmaceutical sector.
  • Regional setbacks in China have prompted large investments to regain ground, and execution risk on those investments could influence near-term returns across international markets and midstream operational plans.

More from Stock Markets

Moscow Stocks Finish Mixed as MOEX Index Holds Steady Feb 22, 2026 Rolls-Royce Poised to Announce Up to £1.5 Billion Share Buyback Alongside Annual Results Feb 22, 2026 DAE Capital Nears Purchase of Macquarie AirFinance, Sources Say Feb 22, 2026 S&P 500 Shows Signs of Tightening Range; Strategist Sees Potential for a Big Move Feb 22, 2026 Supreme Court to Clarify Reach of Helms-Burton Act in Multi-Billion Dollar Cuba Claims Feb 22, 2026