Insider Trading March 19, 2026

Stoke Therapeutics CFO Executes $147,144 Sale to Cover RSU Taxes as Company Advances Zorevunersen Program

Thomas Leggett sold 5,378 shares in mid-March in an issuer-mandated transaction while Stoke reports clinical timeline shifts and receives fresh analyst attention

By Jordan Park STOK
Stoke Therapeutics CFO Executes $147,144 Sale to Cover RSU Taxes as Company Advances Zorevunersen Program
STOK

Stoke Therapeutics Chief Financial Officer Thomas Leggett sold 5,378 shares of company stock on March 17 and 18, 2026, in a series of transactions that generated $147,144. The disposition was reported as an issuer-mandated sale to satisfy tax withholding tied to vested restricted stock units. The trades come amid mixed signals for the company: strong one-year share appreciation, a recent weekly pullback, new analyst coverage and ratings, a substantial CEO bonus approved by the board, and a revised Phase 3 EMPEROR enrollment timeline for lead asset zorevunersen.

Key Points

  • Stoke CFO Thomas Leggett sold 5,378 shares on March 17-18, 2026, generating $147,144 in proceeds at prices between $31.28 and $33.38 per share - the sale was issuer-mandated to cover tax withholding on vested restricted stock units.
  • Post-transaction, Leggett holds 10,172 shares; the stock has been volatile, down 9% over the past week but up 302% over the past year, and InvestingPro flags STOK as slightly overvalued relative to Fair Value.
  • Corporate and clinical updates include a $697,125 discretionary bonus for CEO Ian F. Smith, new Buy coverage from Guggenheim, Cantor Fitzgerald maintaining Overweight, and a revised Phase 3 EMPEROR timeline with enrollment expected Q2 2026 and a mid-2027 data readout.

Thomas Leggett, the Chief Financial Officer of Stoke Therapeutics, Inc. (NASDAQ: STOK), disposed of 5,378 shares of common stock across multiple trades on March 17 and March 18, 2026, according to the Form 4 filing with the Securities and Exchange Commission.

The aggregate proceeds from those transactions totaled $147,144. Trade execution prices spanned from $31.28 to $33.38 per share.

Transaction details filed with the SEC specify the following breakdown:

  • On March 17, Leggett sold 1,274 shares at a weighted average price of $32.7394, with individual sale prices ranging from $31.995 to $32.99.
  • Also on March 17, he sold 922 shares at a weighted average price of $33.3754, with prices ranging from $33.00 to $33.855.
  • On March 18, Leggett sold 2,173 shares at a weighted average price of $31.2838, with prices ranging from $30.59 to $31.58.
  • Additionally on March 18, he sold 172 shares at a weighted average price of $31.7888, with prices ranging from $31.60 to $32.46, and 37 shares at $32.85.

The filing characterizes the sale as an issuer-mandated transaction to satisfy tax withholding liabilities associated with the vesting and settlement of restricted stock units. After these dispositions, Leggett is reported to directly hold 10,172 shares of Stoke Therapeutics common stock.

Market performance surrounding the trades has been volatile. The stock declined 9% over the most recent week even as it has appreciated 302% over the past year. Separately, InvestingPro analysis is cited as indicating that STOK appears slightly overvalued relative to its Fair Value at current levels, and that Pro Research Reports covering STOK and a broad universe of US equities are available for investors seeking more detailed research.

Several other corporate and market developments were disclosed recently that bear on the company’s outlook. Stoke Therapeutics’ Board of Directors approved a discretionary bonus of $697,125 for CEO Ian F. Smith, explicitly recognizing contributions tied to the company’s clinical and financial performance since his appointment.

On the analyst front, Guggenheim has initiated coverage of Stoke Therapeutics with a Buy rating, citing optimism about the company’s lead asset, zorevunersen, which is being developed as a treatment for Dravet syndrome. Cantor Fitzgerald has maintained its Overweight rating as regulatory discussions with the U.S. Food and Drug Administration proceed around potential expedited pathways for zorevunersen.

At the same time, the company disclosed a delay in the Phase 3 EMPEROR study timeline for zorevunersen. Enrollment completion is now expected in the second quarter of 2026, with a data readout anticipated in mid-2027. Stoke Therapeutics plans to begin a rolling New Drug Application submission to the FDA in the first half of 2027.


These items together underscore the mixed signal environment around Stoke Therapeutics: routine insider tax-related selling, significant near- and longer-term clinical milestones for the lead program, active analyst attention, and corporate compensation actions. Investors evaluating STOK will need to weigh the timing of clinical readouts and regulatory interactions alongside current valuation metrics and recent share-price volatility.

Risks

  • Clinical timeline risk - the Phase 3 EMPEROR study for zorevunersen was delayed, with enrollment now expected in Q2 2026 and data readout in mid-2027, potentially impacting near-term regulatory and commercial timelines.
  • Valuation and market risk - despite a substantial one-year gain, the stock has recently pulled back and InvestingPro analysis indicates STOK may be slightly overvalued versus its Fair Value, which could increase sensitivity to negative news or execution misses.
  • Regulatory uncertainty - discussions with the FDA about potential expedited pathways for zorevunersen are ongoing, and outcomes of those discussions could materially affect program timelines and prospects.

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