Insider Trading March 19, 2026

Revolution Medicines CFO Sells $273,869 of Stock as Shares Trade Near 52-Week High

CFO Jack Anders executed a Rule 10b5-1 sale to cover tax obligations; company posts Q4 2025 loss while analysts update coverage and targets

By Priya Menon RVMD
Revolution Medicines CFO Sells $273,869 of Stock as Shares Trade Near 52-Week High
RVMD

Revolution Medicines CFO Jack Anders sold 2,753 shares on March 17, 2026, generating $273,869 in proceeds under a pre-arranged Rule 10b5-1 plan. The move comes as RVMD shares trade close to their 52-week high after a 156% gain year-over-year. The company reported a wider-than-expected Q4 2025 loss driven by higher research and development and SG&A spending, while analysts have issued upbeat coverage and raised price targets amid ongoing clinical programs and a strategic partnership with Royalty Pharma.

Key Points

  • CFO Jack Anders sold 2,753 shares on March 17, 2026, for $99.4804 per share, totaling $273,869.
  • Sale executed under a Rule 10b5-1 plan established May 31, 2023, to cover tax liabilities from RSU vesting; Anders retains 125,512 shares including 56,600 RSUs.
  • Revolution Medicines reported Q4 2025 results with a $1.86 loss per share versus a $1.58 consensus loss; higher R&D and SG&A weighed on results, and the company ended the quarter with $2.03 billion in cash and investments.

Key transaction details

Jack Anders, chief financial officer of Revolution Medicines, Inc. (NASDAQ:RVMD), sold 2,753 shares of the company's common stock on March 17, 2026, according to a Form 4 filing with the Securities and Exchange Commission. The shares were sold at $99.4804 apiece, producing total proceeds of $273,869.

The filing shows the sale was executed under a pre-arranged Rule 10b5-1 trading plan that Anders adopted on May 31, 2023. The plan was established to address tax obligations arising when restricted stock units vest.

Ownership after the sale

Following the disposition, Anders directly holds 125,512 shares of Revolution Medicines. That figure includes 56,600 restricted stock units that remain part of his holdings.

Share price context

The transaction comes as RVMD shares trade near the stock's 52-week high of $124.49, after a reported 156% increase in the past 12 months. InvestingPro analysis noted that the stock is trading near its Fair Value and indicated there are 12 additional ProTips available for subscribers seeking deeper signals about the company's financial positioning.

Recent operating and financial developments

Revolution Medicines reported fourth-quarter 2025 results showing a loss per share of $1.86, wider than the consensus estimate loss of $1.58. The company attributed the shortfall in part to research and development expenses that exceeded expectations by $21.1 million, together with higher selling, general, and administrative costs.

Management reiterated its focus on advancing clinical programs in pancreatic cancer and non-small cell lung cancer, noting the support of a strategic partnership with Royalty Pharma. At quarter end, the company reported $2.03 billion in cash and investments on the balance sheet.

Analyst activity

Recent analyst moves reflect a range of outlooks. UBS initiated coverage with a Buy rating, citing the potential of Revolution's RAS inhibitors in treating various cancers. Piper Sandler raised its price target to $120 and maintained an Overweight rating. Needham trimmed assumptions to set a $145 price target while maintaining a Buy rating despite increased costs. Wells Fargo increased its price target to $144, expressing confidence in the company’s trajectory toward a pivotal readout in 2026.


This article presents the facts of the insider transaction and recent corporate and analyst disclosures. It does not provide investment advice.

Risks

  • Higher-than-expected research and development spending - impacts biotech and healthcare sector capital allocation and near-term profitability.
  • Increased selling, general, and administrative costs contributing to an earnings shortfall - affects valuation perceptions in equity markets and investor confidence.
  • Reliance on clinical program progress and a pivotal readout in 2026 - trial outcomes pose execution risk for the company's strategic outlook and analyst valuations.

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