Insider Trading February 6, 2026

Recursion Pharmaceuticals director undertakes share sales and conversions amid mixed clinical and financial signals

Director sells $164,800 of Class A stock under a 10b5-1 plan; company posts promising TUPELO trial results and receives JPMorgan upgrade

By Maya Rios RXRX
Recursion Pharmaceuticals director undertakes share sales and conversions amid mixed clinical and financial signals
RXRX

Recursion Pharmaceuticals director Christopher Gibson executed a planned sale of Class A shares that generated $164,800 and completed a Class B-to-A conversion, followed days later by a stock-based acquisition to cover tax obligations. The transactions occur against a backdrop of a 45% year-over-year share decline, weak company financial metrics, and encouraging clinical data from the TUPELO trial for REC-4881 that prompted a JPMorgan rating upgrade.

Key Points

  • Director sold 40,000 Class A shares under a Rule 10b5-1 plan and converted 40,000 Class B to Class A on Feb. 4, 2026.
  • On Feb. 6, 30,346 Class A shares were issued to Gibson with 10,364 withheld for taxes at $3.56, totaling $36,895.
  • Positive TUPELO trial data for REC-4881 prompted a JPMorgan upgrade and a December 8, 2025 webinar to present updated data.

Christopher Gibson, a director at Recursion Pharmaceuticals (NASDAQ: RXRX), carried out a programmed disposition of company stock on February 4, 2026, selling 40,000 shares of Class A Common Stock at $4.12 per share for total gross proceeds of $164,800. The sale was executed under a Rule 10b5-1 trading plan, according to regulatory filings.

On the same February 4 transaction date, Gibson also converted 40,000 shares of Class B Common Stock into Class A Common Stock, a structural change in his holdings noted in the paperwork.

A separate filing shows that on February 6 Gibson acquired 30,346 shares of Class A Common Stock, with the company withholding 10,364 shares to meet tax obligations. That issuance was priced at $3.56 per share, representing total consideration of $36,895 tied to the acquisition and withholding arrangement.

Recursion's stock has faced substantial downward pressure over the past year, declining roughly 45% year-over-year. At the time of the filings the share price was quoted at $3.96, slightly below InvestingPro’s Fair Value estimate for the company. InvestingPro data also notes technical indicators - specifically the relative strength index - that suggest the equity is in oversold territory after a 5% decline over the prior week.

Alongside the insider activity, Recursion has been reporting clinical progress. The company announced positive outcomes from the Phase 1b/2 TUPELO trial evaluating REC-4881, a MEK1/2 inhibitor being investigated for familial adenomatous polyposis (FAP). Trial results indicated that 75% of evaluable patients experienced reductions in total polyp burden, with a median reduction of 43% after 12 weeks of treatment. Moreover, 82% of patients who had reductions sustained them 12 weeks after treatment cessation, reflecting a median reduction of 53% from baseline.

Those clinical data points contributed to a change in analyst stance at a major bank. JPMorgan upgraded Recursion from Neutral to Overweight and lifted its price target to $11.00, citing a larger-than-anticipated addressable patient population for REC-4881 as the rationale reflected in its commentary.

Recursion has scheduled a webinar for December 8, 2025, to present updated TUPELO trial data and to offer further details on the safety and efficacy profile of REC-4881 as monotherapy for FAP.

InvestingPro materials referenced in company and market summaries indicate that Recursion has a weak overall financial health score and is rapidly drawing down cash balances, a dynamic highlighted alongside the insider transactions and the clinical developments. Investors looking for expanded analysis can access a Pro Research Report and an additional set of ProTips for RXRX on InvestingPro.


Summary

Recursion director Christopher Gibson sold 40,000 Class A shares under a 10b5-1 plan for $164,800 and converted 40,000 Class B shares to Class A on February 4, 2026. Gibson later received 30,346 Class A shares on February 6, with 10,364 withheld for taxes at $3.56 per share totaling $36,895. These moves coincide with a 45% decline in RXRX over the past year and company-level concerns about cash burn and financial health, even as positive TUPELO trial results for REC-4881 spurred a JPMorgan upgrade and a planned December 8, 2025 webinar to present updated data.


Key points

  • Insider transaction: Director sold 40,000 Class A shares at $4.12 under a Rule 10b5-1 plan and converted 40,000 Class B shares to Class A on February 4, 2026.
  • Subsequent issuance: On February 6, 30,346 Class A shares were acquired by Gibson with 10,364 shares withheld for taxes at $3.56, totaling $36,895.
  • Clinical and analyst developments: TUPELO trial data for REC-4881 showed notable reductions in polyp burden and led JPMorgan to upgrade the stock and raise its $11.00 price target; a webinar on updated data is scheduled for December 8, 2025.

Risks and uncertainties

  • Financial strain: The company is noted to have weak overall financial health and is rapidly consuming cash, which poses liquidity and execution risks for operations and development programs - relevant to investors and capital markets stakeholders.
  • Share price pressure: The stock has fallen about 45% over the last year and is trading below InvestingPro’s Fair Value estimate; technical indicators suggest oversold conditions, but continued volatility is possible, affecting equity investors and traders.
  • Data interpretation and timing: While TUPELO results were positive, further updates are scheduled and market interpretation can change pending the December 8, 2025 webinar and peer review of longer-term safety and efficacy outcomes.

Risks

  • Recursion has a weak overall financial health score and is rapidly burning through cash, creating liquidity risk affecting the company and biotech investors.
  • RXRX shares have declined about 45% year-over-year and remain volatile, which may impact equity holders and market confidence.
  • Further interpretation of the TUPELO data awaits the December 8, 2025 webinar, leaving timing and outcome uncertainties for clinical and commercial prospects.

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