Insider Trading February 18, 2026

Arcellx CFO Disposes $785,000 in Stock; Analysts Offer Mixed Signals on Anito-cel Progress

Michelle Gilson sold 11,291 shares on Feb. 17, 2026, as research firms balance safety data against competitive concerns for Arcellx’s cell therapy program

By Ajmal Hussain ACLX
Arcellx CFO Disposes $785,000 in Stock; Analysts Offer Mixed Signals on Anito-cel Progress
ACLX

Arcellx Chief Financial Officer Michelle Gilson sold 11,291 shares of common stock on February 17, 2026, generating roughly $784,782 in proceeds across two trades. The transactions follow a January restricted stock unit exercise and come amid a flurry of analyst updates that reflect both optimism about preclinical safety signals for the company’s anito-cel therapy and concerns about competitive dynamics.

Key Points

  • CFO Michelle Gilson sold 11,291 Arcellx shares on Feb. 17, 2026, netting about $784,782 across two transactions.
  • Gilson previously acquired 20,496 shares on Jan. 2, 2026, by exercising restricted stock units at $0 per share.
  • Analyst views are mixed: Rothschild Redburn downgraded to Neutral and cut its target, Stifel kept a Buy with a $127 target citing safety signals, and UBS initiated coverage with a Buy and $100 target.

Arcellx, Inc. (NASDAQ: ACLX) reported that Michelle Gilson, the company’s Chief Financial Officer, sold 11,291 shares of Arcellx common stock on February 17, 2026, with the combined transactions valued at approximately $784,782.

The disposition occurred in two separate trades. In the first, Gilson sold 7,141 shares at a weighted average price of $69.2103, with executed prices spanning from $68.69 to $69.68. The second transaction comprised 4,150 shares sold at a weighted average price of $70.0125, with prices in that block ranging from $69.69 to $70.55.

These sales follow an acquisition earlier in the year: on January 2, 2026, Gilson obtained 20,496 shares of Arcellx common stock through the exercise of restricted stock units at a per-share cost of $0.


Analyst activity and program updates

Arcellx has also been the subject of multiple analyst actions and research notes. Rothschild Redburn revised its rating on the company, moving from Buy to Neutral and lowering its price target from $113.00 to $82.00, citing concerns about competition.

In contrast, Stifel retained a Buy rating and set a price target of $127.00, pointing to encouraging safety findings from in vitro work on Arcellx’s anito-cel candidate. Company disclosures indicate that the D-Domain binder used in anito-cel exhibited no tonic signaling or off-target activity in preclinical tests, a detail that was cited as supportive of a favorable safety profile for the CAR T approach.

Arcellx said it intends to present additional data on anito-cel at the 2026 Tandem Meetings, with the forthcoming material expected to address the therapy’s ability to clear tumor cells without engendering prolonged inflammation.

Adding to the coverage mix, UBS initiated coverage of Arcellx with a Buy rating and a $100.00 price target, noting the company’s potential to enter the relapsed/refractory multiple myeloma market by 2026.


Context and takeaway

The combination of an insider sale, a prior personal share acquisition via RSU exercise, and a range of analyst opinions frames a nuanced picture: investors and coverage analysts are parsing encouraging preclinical safety signals alongside worries about a competitive therapeutic landscape. The company’s upcoming presentations at industry meetings will provide further data to evaluate anito-cel’s profile.

Risks

  • Competitive pressure in the cell therapy market - impacts biotechnology and healthcare sectors.
  • Analyst downgrades and differing price targets may increase share price volatility - impacts equity markets and healthcare investors.
  • Pending clinical and preclinical data presentations create uncertainty about anito-cel’s commercial viability and safety profile - impacts biotech investing and oncology therapeutics.

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