Earnings Call Transcripts

Access detailed transcripts and key takeaways from company earnings calls

All Earnings Calls

GH May 7, 2026

Guardant Health Q1 2026 Earnings Call - Revenue Surges 48% as Screening and Oncology Flywheel Accelerates

Guardant Health delivered a breakout first quarter, with revenue jumping 48% year-over-year to $302 million. The growth was broad-based, driven by a 47% surge in oncology test volumes and a massive ex...

  • Total revenue surged 48% year-over-year to $302 million in Q1 2026, marking the fastest YoY growth rate in five years and pushing trailing twelve-month revenue past $1 billion.
  • Oncology revenue grew 36% to $205 million, driven by a 47% increase in test volumes to approximately 86,000, with strong performance across Guardant360 Liquid, Tissue, and Reveal.
  • Shield screening revenue exploded from $6 million to $42 million, fueled by a 44,000-test volume and a successful collaboration with Quest Diagnostics, which expanded market reach.
  • +9 more takeaways
HUBS May 7, 2026

HubSpot Q1 2026 Earnings Call - AI Agents Drive Margin Expansion and Upmarket Growth

HubSpot delivered a resilient Q1 2026, posting 23% reported revenue growth and expanding non-GAAP operating margins by 400 basis points to 18%. The quarter was defined by a strategic pivot toward outc...

  • Q1 2026 revenue grew 23% year-over-year on a reported basis and 18% in constant currency, driven by strong subscription and services growth.
  • Non-GAAP operating margin expanded 400 basis points year-over-year to 18%, reflecting disciplined hiring and FX benefits.
  • Total customer base reached nearly 300,000 globally, adding 10,800 net customers in the quarter.
  • +7 more takeaways
DFTX May 7, 2026

Definium Therapeutics Q1 2026 Earnings Call - Three Phase III Readouts Loom

Definium Therapeutics is entering a high-stakes phase with three pivotal Phase III data readouts for its lead asset, DT120 ODT, scheduled for the second and third quarters of 2026. The company is adva...

  • Definium Therapeutics is approaching a critical inflection point with three pivotal Phase III data readouts for DT120 ODT scheduled for Q2 and Q3 2026.
  • The Emerge study in major depressive disorder (MDD) is complete with 149 participants and will report top-line data later this quarter.
  • Two Phase III studies in generalized anxiety disorder (GAD), Voyage and Panorama, will report top-line data in Q3, with Panorama having exceeded its enrollment target.
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ZYME May 7, 2026

Zymeworks Q1 2026 Earnings Call - Regulatory Catalysts and RAS ADC Pipeline Expansion

Zymeworks is approaching a critical inflection point with the August 25, 2026 PDUFA date for zanidatamab in first-line GEA and an sBLA filing in China. These milestones unlock $300 million in near-ter...

  • The August 25, 2026 PDUFA date for zanidatamab in first-line GEA marks a pivotal near-term catalyst, with a $250 million milestone payment from Jazz upon U.S. approval.
  • An sBLA filing has been submitted in China for first-line GEA, triggering a $50 million milestone payment from partner BeOne upon approval.
  • Revenue fell to $2.4 million in Q1 2026 from $27.1 million in Q1 2025, driven by the absence of non-recurring clinical milestones from the prior year.
  • +7 more takeaways
AKAM May 7, 2026

Akamai Technologies Q1 2026 Earnings Call - $1.8 Billion AI Infrastructure Win Signals Shift to Distributed Inference Grid

Akamai Technologies delivered a strong Q1 2026, driven by a record $1.8 billion seven-year cloud infrastructure deal with a frontier AI model company. This landmark contract, alongside a $200 million ...

  • Akamai secured a historic $1.8 billion, seven-year cloud infrastructure services contract with a leading frontier AI model company, marking the largest deal in the firm’s history.
  • Cloud Infrastructure Services (CIS) revenue surged 40% year-over-year to $95 million in Q1, reflecting rapid adoption of Akamai’s distributed AI inference platform.
  • Total Q1 revenue reached $1.074 billion, up 6% year-over-year, with security revenue growing 11% and delivery revenue declining 7% due to the Edgio transaction.
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ALTG May 7, 2026

Alta Equipment Group Q1 2026 Earnings Call - Q1 Weakness Masks Strong Booking Inflection and Margin Recovery

Alta Equipment Group reported a disappointing Q1 2026, with revenues falling 3% year-over-year to $410.5 million and adjusted EBITDA coming in at $28.1 million. The miss was driven by a perfect storm ...

  • Q1 revenues fell 3% year-over-year to $410.5 million, with adjusted EBITDA of $28.1 million missing internal expectations due to seasonal headwinds and tax-driven pull-forward sales in Q4 2025.
  • Material Handling segment revenues declined 4.7% to $150.5 million, driven by soft used equipment sales, but bookings surged to their strongest level since June 2023, signaling a clear inflection point.
  • Construction Equipment revenues remained flat at $244.3 million, supported by strong quoting activity and fully funded state and federal infrastructure spending, despite a delayed start to the seasonal construction cycle.
  • +7 more takeaways
GMED May 7, 2026

Globus Medical Q1 2026 Earnings Call - Margin Expansion and EPS Guidance Hike

Globus Medical delivered a robust Q1 2026, with revenue rising 27% to $759.9 million and non-GAAP EPS jumping 64.7% to $1.12. The company is clearly executing on its integration and margin expansion p...

  • Q1 2026 revenue reached $759.9 million, a 27% increase year-over-year, driven by strong performance across US Spine, International Spine, and Trauma.
  • Non-GAAP EPS surged 64.7% to $1.12, beating expectations and prompting management to raise full-year EPS guidance to $4.70-$4.80.
  • Adjusted gross profit margin remained resilient at 69.2% despite a typical seasonal Q1 decline, highlighting successful manufacturing and supply chain synergies.
  • +7 more takeaways
OPRT May 7, 2026

Oportun Financial Corporation Q1 2026 Earnings Call - New CEO Reiterates Full-Year Guidance Amid Tight Credit Posture

Oportun Financial reported a cautious Q1 2026, marked by an 11% decline in originations and a 12.65% annualized net charge-off rate, the midpoint of guidance. The new CEO, Doug Bland, arrived less tha...

  • New CEO Doug Bland, who joined less than three weeks ago, chose to reiterate the full-year 2026 guidance rather than announce a new strategy, citing the need for a deeper assessment of the business foundation.
  • Originations declined 11% year-over-year in Q1, driven by seasonality and a strategic shift toward returning members, who now account for 79% of originations compared to 63% in the prior year quarter.
  • The annualized net charge-off rate came in at 12.65%, the midpoint of guidance, but management expects this to be the highest rate of 2026, with delinquency rates improving sequentially.
  • +10 more takeaways
ATGE May 7, 2026

Covista Q3 2026 Earnings Call - Chamberlain Returns to Growth, Guidance Raised Amid Structural Healthcare Labor Shortage

Covista delivered a strong third quarter, driven by enrollment momentum across Chamberlain, Walden, and its medical and veterinary segments. Chamberlain returned to positive total enrollment growth ah...

  • Covista surpassed 100,000 total students with 11 consecutive quarters of growth, marking a structural inflection point in its national healthcare education platform.
  • Chamberlain returned to positive total enrollment growth (0.5%) ahead of plan after fixing marketing effectiveness and funnel conversion issues, with application volumes and conversion rates normalizing to historical levels.
  • Walden University set a new enrollment record with 12.3% growth to over 54,000 students, driven by broad-based program gains and improved first-to-second semester retention.
  • +7 more takeaways
INGN May 7, 2026

Inogen Q1 2026 Earnings Call - International Growth and Pipeline Expansion Offset U.S. Rental Pressure

Inogen delivered Q1 2026 revenue of $85.1 million, beating expectations as international sales surged 18% year-over-year, more than compensating for a 5% decline in U.S. sales. The company is navigati...

  • Total revenue reached $85.1 million, up 3.4% year-over-year, beating management expectations.
  • International sales surged 18% year-over-year to $37.7 million, driven by strong execution in Eastern Europe, Latin America, and Asia Pacific.
  • U.S. sales declined 5% to $34.7 million, pressured by a structural shift where 60% of new long-term patients now start on POCs, hurting direct-to-consumer and rental channels.
  • +10 more takeaways