Analyst Ratings February 25, 2026

TD Cowen Starts Coverage of Century Therapeutics With Buy Rating

Analyst highlights CNTY-813 as a potentially transformative allogeneic cell therapy for type 1 diabetes; recent financing and analyst moves bolster outlook

By Derek Hwang IPSC
TD Cowen Starts Coverage of Century Therapeutics With Buy Rating
IPSC

TD Cowen has begun coverage of Century Therapeutics with a Buy rating, pointing to the company’s lead candidate CNTY-813 — an allogeneic insulin-expressing beta islet cell therapy for type 1 diabetes — as central to long-term value creation. CNTY-813 has produced preclinical data and is slated to enter clinical trials in 2026 with initial data expected in 2027. Recent financing and analyst updates have also influenced the company’s near-term financial visibility and market sentiment.

Key Points

  • TD Cowen initiated coverage with a Buy rating, emphasizing CNTY-813 as the lead program - impacts biotech and healthcare investment sectors.
  • CNTY-813 is an allogeneic insulin-expressing beta islet cell therapy for type 1 diabetes with preclinical data; clinical entry expected in 2026 and initial data in 2027 - impacts clinical development timelines and biotech R&D planning.
  • Century completed a $135 million private placement extending cash runway to Q1 2029; several analysts adjusted price targets and ratings - impacts capital markets and investor sentiment in the biotech sector.

TD Cowen has initiated coverage of Century Therapeutics with a Buy rating, citing the company’s focus on allogeneic stem cell therapies and its lead candidate, CNTY-813. The therapy is an allogeneic insulin-expressing beta islet cell treatment being developed for type 1 diabetes.

CNTY-813 has generated preclinical data, and Century Therapeutics plans to begin clinical testing in 2026, with the expectation of initial clinical readouts in 2027. TD Cowen analyst Phil Nadeau summarized the firm’s view in a comment that highlights the program’s potential:

"Century develops potentially curative allogeneic stem cell therapies. Century’s lead is CNTY-813, an allogeneic insulin-expressing beta islet cell therapy for type 1 diabetes that has produced intriguing preclinical data. It is expected to enter the clinic in 2026 and generate initial data in 2027."

Market reaction to Century Therapeutics has been pronounced over the past year. The stock has rallied more than 200% in the last 12 months and surged 317% over the most recent six-month period, valuing the company at a market capitalization of $382.65 million. Analysts covering the company have set price targets that span from $2 to $6, and one platform’s analysis indicates the shares may still be slightly undervalued at current levels.

Investor support for the company’s clinical ambitions has been reinforced by a recent private placement that raised $135 million. Management says that proceeds from this financing are intended to support development of CNTY-813 and extend Century Therapeutics’ cash runway to the first quarter of 2029.

Other firms have maintained or adjusted their views in recent weeks. Clear Street reiterated a Buy rating with a price target of $6.60 while noting the potential of CNTY-813 as a cell therapy; that firm had previously reduced its price target from $8.00 to $6.60 but continues to rate the stock Buy. Piper Sandler raised its price target from $2.00 to $4.00 and kept an Overweight rating, citing the value contributions from Century’s expanded pipeline, which includes CNTY-308 alongside CNTY-813.

TD Cowen expects the company to deliver long-term shareholder value as its pipeline advances through development. The combination of preclinical progress for CNTY-813, a planned entry into clinical trials in 2026, recent financing, and multiple analyst updates has shaped the current market narrative around the company.


Summary

TD Cowen has initiated coverage of Century Therapeutics with a Buy rating, highlighting CNTY-813 — an allogeneic insulin-expressing beta islet cell therapy for type 1 diabetes — which has produced preclinical data and is expected to enter clinical trials in 2026 with initial data in 2027. The company recently completed a $135 million private placement that extends its cash runway to Q1 2029, and other analysts have adjusted price targets and ratings in light of the company’s pipeline developments.

Risks

  • Clinical and regulatory uncertainty - CNTY-813 is still at the preclinical stage with clinical entry expected in 2026 and initial data in 2027, so development and approval risks remain for the biotech and healthcare sectors.
  • Valuation volatility - the stock has rallied sharply (over 200% in the past year and 317% in the past six months), creating potential market sensitivity to trial outcomes or analyst revisions impacting investors and financial markets.
  • Dependence on financing and pipeline progress - while a $135 million private placement extends the cash runway to Q1 2029, continued development of CNTY-813 and other programs may require further capital or successful clinical milestones affecting capital markets and company operations.

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