Analyst Ratings February 24, 2026

BofA Increases Beam Therapeutics Price Target to $47 Citing Pipeline Advances

Broker keeps Buy rating as company progresses liver-targeted programs and secures financing; near-term clinical readouts and FDA pathway alignment highlighted

By Sofia Navarro BEAM
BofA Increases Beam Therapeutics Price Target to $47 Citing Pipeline Advances
BEAM

BofA Securities raised its price target for Beam Therapeutics Inc. (BEAM) to $47 from $45 while maintaining a Buy rating. The firm pointed to updates across Beam’s liver-targeted in vivo editing platform - including a new PKU program, momentum in a Pfizer collaboration, and FDA alignment on an accelerated pathway in AATD - as underpinning the move. Beam’s shares have climbed 70% over the past six months, and the company reports a stronger cash position than debt alongside new non-dilutive financing to support its pipeline.

Key Points

  • BofA raised its price target on BEAM to $47 from $45 while maintaining a Buy rating - impacts biotech and capital markets sectors.
  • Company updates include a new liver-targeted program BEAM-304 for PKU and progress in the Pfizer collaboration - affects clinical development and partnership valuation.
  • Beam has stronger cash than debt and announced non-dilutive financing - relevant to investors assessing balance-sheet resilience and funding for R&D.

Overview

BofA Securities has increased its price target on Beam Therapeutics Inc. (NASDAQ: BEAM) to $47 from $45 and left its Buy rating unchanged. At the time of the announcement, the stock was trading at $31.26, while analyst target prices on the name span a wide $22 to $80 range. Beam’s shares have risen roughly 70% over the last six months, reflecting growing investor interest in the company’s gene-editing platform.

Drivers cited by BofA

BofA pointed to a series of updates tied to Beam’s liver-targeted in vivo editing platform. Those updates include the introduction of a new program, BEAM-304, aimed at treating phenylketonuria (PKU), and reported progress within the company’s collaboration with Pfizer. The bank said these developments reinforce the long-term value potential of Beam’s underlying technology.

The analyst note also emphasized near-term milestones. Beam is expected to provide updated phase 1/2 data for BEAM-302 and outline next steps for that clinical program in the first quarter of 2026. In addition, BofA described recent FDA alignment on a potential accelerated approval pathway in alpha-1 antitrypsin deficiency (AATD) - an approach that would assess biomarkers over a 12-month window - as a meaningful regulatory development for the company.

Clinical and operational updates

Beam plans to enroll approximately 50 additional patients in its AATD program. To support its clinical efforts, the company announced a non-dilutive capital agreement intended to help fund its pipeline. According to InvestingPro data cited by the analyst, Beam’s balance sheet currently shows more cash than debt, a position that BofA said enhances the company’s financial flexibility.

Valuation and financial context

BofA noted that its revised $47 target reflects Beam’s present cash position and assumptions about forthcoming license revenue. The firm continues to track both the clinical readouts and the company’s funding posture as inputs to its valuation.

Recent earnings and market reaction

Beam reported financial results for the fourth quarter of 2025 and used its earnings call to highlight strategic initiatives and product development progress. Those disclosures prompted a positive market response, according to the reporting, though specific revenue and earnings figures were not provided in the discussion. The commentary around the earnings call was characterized as optimistic, and no analyst upgrades or downgrades were noted in the reports referenced. Beam’s recent clinical, regulatory and financing actions remain under close observation by investors.

Additional resources

For investors seeking a deeper, model-driven look at valuation and prospects, the company’s Pro Research Report is available, along with similar reports covering more than 1,400 other U.S. equities.


Note: The article presents developments and statements as reported; it does not include undisclosed revenue or earnings figures beyond those referenced.

Risks

  • Clinical readouts timing and outcomes - the BEAM-302 phase 1/2 data and subsequent development decisions expected in Q1 2026 could materially affect valuation; this risk impacts biotech investors and equity markets.
  • Regulatory uncertainty - while the FDA alignment on a potential accelerated approval pathway in AATD was noted as positive, the pathway still involves evaluation of biomarkers over 12 months and carries regulatory risk for the program and market expectations.
  • Financing and execution risk - although Beam has more cash than debt and has secured a non-dilutive agreement, the company’s ability to execute on enrollment, trials and licensing revenue assumptions affects funding and R&D progress, influencing biotech and capital markets.

More from Analyst Ratings

Wedbush Keeps Outperform on IBM After Steep Drop Tied to Anthropic Announcement Feb 24, 2026 Leerink Keeps Outperform on Fulcrum After Full PIONEER Phase 1b Data; Price Target Unchanged Feb 24, 2026 Baird Lowers Highwoods Properties Price Target, Flags Longer Growth Timeline Feb 24, 2026 Rosenblatt Reaffirms Buy on AMD After Expanded Meta Agreement Feb 24, 2026 BofA Holds Underperform on Fulcrum Therapeutics, $7 Target Stays Despite Clinical Progress Feb 24, 2026