Johnson & Johnson is moving forward with preparations for a potential sale of its orthopedics division, DePuy Synthes, according to a report that cited people familiar with the matter. Large buyout firms are among the interested parties, and the business could fetch in excess of $20 billion if it is put on the market.
The company is compiling documents and financial statements for DePuy Synthes as it plans meetings with prospective buyers in the coming weeks. Multiple large private equity firms are reportedly considering forming partnerships to mount a bid for the unit, and the process could also draw interest from competing medical device manufacturers.
DePuy Synthes manufactures hip, knee and shoulder implants, surgical instruments and other related products. The orthopedics business generated $9.3 billion in sales in 2025, according to the information released.
Last year, Johnson & Johnson announced plans to carve out its orthopedics business into a standalone company within the next 18 to 24 months, representing the corporation's second significant spinoff in two years as it narrows its focus on higher-growth segments of healthcare. The company did not immediately respond to a Reuters request for comment.
Joe Wolk, Johnson & Johnson's chief financial officer, has previously said the company is weighing multiple routes for the separation, with a tax-free spinoff identified as the primary option. He also noted that the separation is already in progress and that he did not expect any further material updates on the transaction until mid-2026.
Context and near-term steps
J&J's current activity centers on preparing a formal packet of financials and related documentation for DePuy Synthes. Those materials are expected to support initial discussions with potential buyers scheduled over the coming weeks, as the company explores sale and separation pathways while continuing its previously announced timeline for a standalone orthopedics entity.
Market and strategic implications
The potential divestiture would mark another major structural change for Johnson & Johnson and could reshape competitive dynamics within medical devices, particularly in the orthopedics sector. Interest from buyout firms, sometimes in consortiums, as well as from rival device makers, reflects the strategic and financial value attached to established implant and surgical-instrument portfolios.