Press Releases March 29, 2026

BeyondSpring Announces Plinabulin and ADC Combination Poster Presentation at AACR Annual Meeting 2026

BeyondSpring to Present Data on Plinabulin and Antibody-Drug Conjugate Combination at AACR 2026

By Derek Hwang BYSI
BeyondSpring Announces Plinabulin and ADC Combination Poster Presentation at AACR Annual Meeting 2026
BYSI

BeyondSpring Inc., a clinical-stage biopharmaceutical company, announced a poster presentation at the 2026 AACR Annual Meeting showcasing data on the combination of Plinabulin with antibody-drug conjugates and immune checkpoint inhibitors, highlighting enhanced antitumor efficacy. This presentation underscores Plinabulin's potential in cancer immunotherapy and its unique immune modulation mechanisms.

Key Points

  • BeyondSpring will present data on Plinabulin enhancing antitumor efficacy when combined with topoisomerase inhibitor-based antibody-drug conjugates, both with and without immune checkpoint inhibitors.
  • Plinabulin is in late-stage clinical development targeting non-small cell lung cancer (NSCLC) and operates via a novel dendritic cell maturation mechanism to modulate immune response.
  • The AACR Annual Meeting provides a critical platform to showcase the therapeutic potential and advancing clinical profile of Plinabulin in oncology treatment modalities.

FLORHAM PARK, N.J., March 30, 2026 (GLOBE NEWSWIRE) -- BeyondSpring Inc. (NASDAQ: BYSI) (“BeyondSpring” or the “Company”), a clinical-stage company developing transformative therapies for the treatment of cancer and other diseases, today announced that the Company will have a poster presentation at the 2026 Annual Meeting of the American Association for Cancer Research ("AACR"), taking place on April 17 through 22, 2026 in San Diego, California.

Presentation Details:

  • Title: Plinabulin Boosts Antitumor Efficacy of Topoisomerase Inhibitor-based Antibody-drug Conjugates Without or With Immune Checkpoint Inhibitor
  • Presenter / Authors: Yingjuan June Lu, Xiaoyan He, Weiwei Cheng, Zhengyan Zhang, James Tonra, Lan Huang
  • Presentation Time: April 21, 2026, 2PM to 5PM PT
  • Location: Poster Section 8 at San Diego Convention Center
  • Session Category: Immunology
  • Session Title: T Cell Engagers 2 / Antibody-Drug Conjugates 1
  • Poster Board Number: 16
  • Poster Number: 5597

About BeyondSpring
BeyondSpring (NASDAQ: BYSI) is a clinical-stage biopharmaceutical company developing first-in-class therapies addressing high unmet medical needs. Its lead asset, Plinabulin, is in late-stage clinical development as an anti-cancer agent in NSCLC and other indications. Plinabulin’s novel mechanism as a dendritic cell maturation agent supports both anti-cancer activity and immune modulation, offering a unique approach to restoring tumor sensitivity to checkpoint inhibitors. Learn more at https://beyondspringpharma.com.

Investor Contact: [email protected]
Media Contact: [email protected]


Risks

  • Clinical trial data presented may not fully translate into successful regulatory approvals or commercial success, posing uncertainties for Plinabulin's market potential.
  • Combining Plinabulin with other agents may present unforeseen safety or efficacy challenges impacting ongoing development.
  • Investor expectations might be heightened by presentation news, but actual clinical outcomes and market adoption remain uncertain, affecting stock performance.

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