Insider Trading April 6, 2026

Pelthos Director Sells 797 Shares Under 10b5-1 Plan as Company Posts Mixed Financials

Peter Greenleaf executed two stock sales totaling $16,669; Pelthos reported a sizable EPS miss but rising revenue and product sales following ZELSUVMI launch

By Hana Yamamoto PTHS
Pelthos Director Sells 797 Shares Under 10b5-1 Plan as Company Posts Mixed Financials
PTHS

Pelthos Therapeutics director Peter Greenleaf sold 797 shares of company stock on April 2, 2026, under a pre-arranged 10b5-1 plan for $16,669. The company posted a fourth-quarter 2025 EPS well below expectations, though quarterly revenue and 2025 net product revenue climbed on the back of a mid-year product launch. Analyst coverage was unchanged in rating and saw a modest price-target increase.

Key Points

  • Director Peter Greenleaf sold 797 Pelthos shares on April 2, 2026, under a 10b5-1 plan for total proceeds of $16,669.
  • Pelthos reported a Q4 2025 EPS of -6.87, missing the forecasted -0.54, while revenue rose 28% quarter-over-quarter to $9.1 million.
  • Oppenheimer raised its price target to $62 from $60 and maintained an Outperform rating; Pelthos reported $16.2 million in net product revenue for 2025 following the mid-year drug launch.

Director Peter Greenleaf disclosed the sale of 797 shares of Pelthos Therapeutics Inc. common stock (NASDAQ: PTHS) on April 2, 2026, via a Form 4 filed with the Securities and Exchange Commission. The transactions were carried out under a pre-established 10b5-1 trading plan and generated proceeds of $16,669 in total.

The divestiture was split into two trades. The first transaction moved 420 shares at a weighted average price of $20.5151, with execution prices spanning $20.30 to $20.78. The second involved 377 shares at a weighted average price of $21.3614, with prices ranging from $21.31 to $22.03. After these sales, Greenleaf directly holds 24,681 shares of Pelthos Therapeutics.

Following the trades, the stock has traded higher and most recently reached $24.38, although it remains nearly 3% lower on a one-week basis. Analysis on InvestingPro indicates that Pelthos shares appear overvalued compared with that platform's Fair Value assessment.


Alongside the insider activity, Pelthos released financial results that paint a mixed picture for the company. For the fourth quarter of 2025, Pelthos reported an earnings per share of -6.87, which missed consensus expectations of -0.54. Despite the earnings shortfall, the company recorded a 28% sequential increase in revenue, with quarterly sales of $9.1 million.

Pelthos also reported net product revenue of $16.2 million for the full year 2025, a figure tied to the mid-year commercial introduction of its drug. Broker Oppenheimer adjusted its price target modestly to $62 from $60 while keeping an Outperform rating, citing the company’s progress related to the ZELSUVMI rollout.

On the development front, Pelthos announced that the first patient has been dosed in a Phase 1b/2a clinical trial for CT2000, an investigational therapy aimed at treating eye pain. That trial is being executed by Channel Pharmaceutical Corporation, a Pelthos subsidiary. Together, these items reflect the company’s ongoing operational, commercial, and clinical activities.


The disclosed insider sale, the financial results that mixed revenue growth with an EPS miss, and the continued clinical progress together form the immediate factual landscape for Pelthos. Market participants may weigh the director's sale alongside the company’s recent performance and valuation assessments.

Risks

  • Significant earnings miss in Q4 2025 - the EPS of -6.87 fell well short of the expected -0.54, indicating potential profitability and cost challenges; this primarily affects the healthcare and biotech sectors.
  • Valuation concerns highlighted by InvestingPro, which indicates shares appear overvalued relative to its Fair Value assessment - a risk for equity investors and capital markets participants.
  • Share-price variability - the stock rose to $24.38 after the sale but was down nearly 3% over the past week, reflecting potential volatility in investor sentiment within pharmaceutical equities.

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